Faculty of Health Science كلية العلوم الصحيه
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Item 6th of october faculty of medicine(جامعة الشيخ عبدالله البدري, 2008) mohammed fat7y6th of october faculty of medicineItem A Case of Antithyroid Drug-Induced Agranulocytosis Pre-Covid 19 Era(جامعة الشيخ عبدالله البدري, 2020) Sufian K. M. Noor; , Mosab Nouraldein Mohammed Hamad; , Sarra Osman Bushara; , Amel Abdalrhim Sulaiman3; Mohamed Adil Yassen Ali4; , Remaz Khalid Hassan Ahmed4; , Almotasim Mohamed Aabdelmgid Elnaema; Samaher Mozamil Mohamed AbdelrahimAgranulocytosis is an infrequent and serious side effect of antithyroid drugs characterized by a noticeable reduction in granulocyte and neutrophil count, it usually occurs within the first 2-3 months of treatment. There is a variety of mechanisms by which ATD can induce agranulocytosis, direct drug effects, and immunological mechanisms. We present 33 years old female attended Atbara teaching hospital who has developed agranulocytosis 2 weeks after starting ATD to treat relapsed Graves’ disease. What was unusual about this patient is that symptoms have occurred in a period less than 15 days of starting treatment and with a dose of 45 mg/day. The physician must educate the patient about the possibility of early onset of serious side effects of ATD and to seek medical advice as soon as possibleItem A COMPARATIVE HORMONAL STUDY FOR TWO TYPES OF AMNIOTIC ANIMALS(2021-10-12) بقاء حازم إسماعيل; رشيد محمد رشيد; لينا صالح عبد المطلبABSTRACT This research aims to study thyroid hormones, growth hormone, and estrogen hormone in two types of Iraqi amniotes. The study included two types of Mature animals, the local rabbit (Oryctolagus cuniculus), an example of mammals, and the Japanese quail (Coturnix coturnix Japanese), an example of birds. Twenty females were taken from each of the rabbits and quails, and they were of sexual maturity and weighed(1347.2 ± 404.2) g and (173.5 ± 42)g respectively. The level of thyroid function T3, T4, TSH, growth hormones (GH), and estrogen (E2) was measured in the blood serum of quail and local rabbit using ELISA technique following the steps in the leflet kit supplied by the company MY BioSource and CUSABIO. The results of the current study.showed a significant increase in the concentration of T3, T4, TSH, and estrogen hormones in the rabbit compared to the quail at a probability of (p≤0.01). The study also showed a Highly significant increase of growth hormone in rabbit serum compared with the quail at probability of (p≤0.05). يهدف البحث الى دراسة مقارنة لهرمونات الدرقية وهرمون النمو وهرمون االستروجين لنوعين من الحيوانات السلوية العراقية. شملت الدراسة نوعين من الحيوانات هي االرنب المحلي كمثال على اللبائن والسمان الياباني كمثال على الطيور. تم اخذ 20 انثى من كل من االرانب والسمان وكانت في عمر النضج الجنسي وبوزن )42. 173.5±( و)404.2 ± 1347.2)غرام على التوالي. تم تقدير تركيز هورمونات الدرقية3T و4T وTSH وهرمون النمو واالستروجين في مصل دم الطيور السمان واالرانب باستعمال تقنية االليزا ELISA وفقا للطريقة المرفقة مع عدة القياس المجهزة من شركة CUSABIO ,BioSource MY . أظهرت نتائج الدراسة الحالية ارتفاع معنوي في تركيز هرمون TSH 4,T 3,T واالستروجين في االرانب بالمقارنة مع طيور السمان وعند نسبة احتمال (0.01≥p). )كما أظهرت الدراسة وجود ارتفاع معنوي لهرمون النمو في مصل دم االرنب بالمقارنة مع طير السمان عند نسبة احتمال (0.05≥p).)Item A perspective influence of the Epsilon variant of COVID-19 on Catechol-O-Methyltransferase Val158Met leads to the emergence of human papilloma virus-Gueye, which is wrongly described as monkey pox(جامعة الشيخ عبدالله البدري, 2022) Mosab Nouraldein Mohammed HamadAbstract A perspective study discussed how the epsilon variant of COVID-19 induced mutation to the existed human papilloma virus via mutagenic cadmium content of the COVID-19, and arsenic content of epsilon variant lead to appearance of new strain of human papilloma virus, we named it Human Papilloma Virus-Gueye. As this virus is most common among gay men, and due to the absence of infection with it among HIV-controlled patients. We suggest that this virus disturbs Catechol-O-Methyltransferase Val158Met which is the region which is responsible for male sexual orientation and has been linked to executive dysfunction, which might increase sexual risk behaviours favouring HIV transmission, which is damaged by mycotoxin of myecetoma fungal species and by cadmium contents of epsilon variant of COVID-19. We conclude that COVID-19 is not hazardous just because of its severe symptoms , but also because of its action as a mutagen on other microbes that may be present in a subclinical state. Also, we suggest that immunization against COVID-19 may lead to unexpected complications, especially mutations in other microbes. Finally, we claim that the scientific community named it monkey pox. Even among individuals who do not travel to the endemic, it is just mutant form of Human Papilloma virus.Item A rare case of calcinosis cutis in rheumatoid arthritis(جامعة الشيخ عبدالله البدري, 2020-12-02) Wafaa Hassan Ahmed Albashir; Rihab Mohamed Hassan Ali,; Sufian Khalid M Nor,; Sara yassin,; Mosab Nouraldein Mohammed HamadAbstract Calcinosis cutis is a rare disorder characterized by of deposition of insoluble calcium salts in the skin and subcutaneous tissue. Five subtypes of calcinosis cutis are described: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis.1 Of these subtypes, dystrophic calcinosis (DC) is the most common, and it is the most frequently seen in association with underlying autoimmune connective tissue diseases.2 Dermatomyositis, systemic sclerosis and less commonly systemic lupus erythematous were described to be complicated by DC. However, DC associated with rheumatoid arthritis (RA) is extremely rare.2 The condition causes substantial morbidity and is associated with pain and limitation of movement when the process involves areas close to joints or when ulceration occurs.2 We report a middle age Sudanese woman with good controlled RA who developed dystrophic calcinosis cutis.Item ABO and Rhesus Grouping among Sudanese Patients with Coronary Artery Disease at Sudan Heart Center-Khartoum State(جامعة الشيخ عبدالله البدري, 2019) Mosab Nouraldein Mohammed HamadAbstract Background: Many reports have appeared in recent years suggesting an association between blood groups and various manifesta tions of heart diseases. Many risk factors have been suggested as risk factors for Coronary Heart Disease. Among them is the ABO blood grouping. Materials and Methods: This a descriptive analytical study aimed to determine the frequency of blood group and Rhesus factor of patients with cardiovascular diseases at Khartoum state, during the period from October 2018 to March 2019. Five hundred patients with coronary artery diseases attended Sudan center of Heart and 500 apparently healthy controls were enrolled in this study. An informed consent was obtained from each participant before blood sample collection. ABO and Rh factor were performed by slide techniques using specific anti-sera. Thereafter, data was analyzed and organized by Microsoft Excel and SPSS computer program. Results: The results showed that most common blood group in patients with coronary artery diseases was O followed by A, and then B and least frequent was AB. Majority of patients with coronary artery diseases were Rh positive. Most common blood group was O (44.2%) followed by A (30.4%) and then B (21.4%) and least frequent was AB (4%). Finally, the results of the present study showed that there is no association of ABO blood group and Rh factor with cardiovascular diseases. Although the frequent of coronary artery diseases was higher in O group, the difference was statistically insignificant. We noticed that there’s an association between Coronary heart disease and ABO blood group due to the result of the P value (0.0003). Conclusion: We concluded that the risk of Coronary heart disease for individuals with non O blood grouping is higher than that of people with O blood grouping. And no association of Rhesus factors with Coronary Heart disease.Item Acinetobacter Baumanni in Ciconia Ciconia As Potential Host for Coronavirus Strains(جامعة الشيخ عبدالله البدري, 2021-02-01) Mosab Nouraldein Mohammed HamadAbstract Acinetobacter baumanni in white storks (Ciconia ciconia) is the main host of coronavirus strains and can convert coronavirus from each strain to another, the occurrence of outbreaks of SARS CoV-2 VUI 202012/01, in a year of the reappearance of white storks in England, the concentration of new variant strain of coronavirus in the south-east part of Britain, huge amount of visitors to hatched white storks and presence of Acinetobacter baumanni in nesting of this endangered migratory bird, power the linkage between bacteria, virus and bird. Furthermore, outbreaks of Middle East respiratory syndrome in Saudi Arabia after the death of a huge amount of white storks in the southern area of Jeddah city, certainly Wadi Al-Dawasir Province, and later outbreak of MERS in Saudi Arabia with more concentration in Wadi Al Dawasir. Also artificial nesting of white storks in The Honghe Nature Reserve in northeast China's Heilongjiang province and Acinetobacter baumanni outbreaks in China predisposing factors for SARS COV-1 and SARS COV-2. Overlapping coding sequencing is required to follow up the potential relation between coronavirus strains, Acinetobacter baumanni and the white storks.Item ACTINOMYCES(جامعة الشيخ عبدالله البدري, 2023) Mosab Nouraldein Mohammed HamadDistinguishing Features: Anaerobic Branching rods Non−acid fastItem allergy overview(جامعة الشيخ عبدالله البدري, 2018) Mosab Nouraldein Mohammed HamadAn allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies often are sensitive to more than one thing. Substances that often cause reactions are Pollen 'XVWPLWHV 0ROGVSRUHV 3HWGDQGHU )RRG ,QVHFWVWLQJV 0HGLFLQHV Normally, your immune system fights germs. It is your body's defense system. In most allergic reactions, however, it is responding to a false alarm. Genes and the environment probably both play a role. Allergies can cause a variety of symptoms such as a runny nose, sneezing, itching, rashes, swelling, or asthma. Allergies can range from minor to severeItem Alteration of Coagulation Parameters in Plasmodium Falciparum Malaria Patients and its Correlation with Degree of Parasitaemia in Khartoum state Sudan; 2019(جامعة الشيخ عبدالله البدري, 2019-12-30) Rawan Abdullah Ibrahim Abdullah; , Mosab Nouraldein Mohammed Hamad; , Sahar Eldirderi Gafar Osman; Tamer Imad AldeenTaha Mahmoud; Ehab Mohammed Elmadenah Mohammed AhmedBackground: The hemostatic alterations play an important role in malaria pathogenesis and in the progression of disease. In severe infection the accelerated coagulation cascade activity with accelerated fibrinogen turnover increase the bleeding tendency and may lead to DIC. Objectives: This study was aimed to determine the Alteration of coagulation parameters in Plasmodium Falciparum malaria Patients and its correlation with degree of parasitemia in Khartoum state. Sudan; 2019. Material and method: Analytical cross sectional study, 170 blood samples were enrolled in this study.85 samples of blood were collected from patients with falciparum malaria and 85 samples were collected from healthy individual as control, then PT and APTT will be measured by coagulometer. Result: The mean of PT was significantly high in case than in control (14.201second vs 13.668 second, (P value (< 0.01)).While there was no differences in the mean of APTT between case and control (33.075 vs 33.192 second ) P value (0.735). Conclusions: Our study concluded that the mean of PT was significantly higher in case than control, While there was no differences in the mean of APTT between case and control, and There was no differences between the PT and APTT of case and control according to gender. And there is no correlation between degree of parasitemia in PT, APTT and age.Item Anemia and Women Subfertility(جامعة الشيخ عبدالله البدري, 2019) Mosab Nouraldein Mohammed HamadAnemia is a condition in which the blood hemoglobin (the main oxygen-transporting protein in red blood cells) level is under the minimum extreme of the reference range for the age and gender of the person .It is the most common hematological disorder affects millions of women at reproduction period around the globe that may influence in different phases of their socioeconomic lifestyle. It occurs due to increase red blood cell destruction or due to bone marrow failure to produce adequate number of blood cells. Iron deficiency anemia is the most common type of anemia noticed among women during their reproductive age, while other types are less common. Pernicious anaemia and folate deficiency are recognized to cause secondary infertility. Any attempts to treat infertility or to even establish preliminary investigations should be delayed until anaemia is treated. Management of anaemia itself may resolve the infertility problems and should be taken as a first line treatment in all cases.Item Anemias in children(جامعة الشيخ عبدالله البدري, 2020) Mosab Nouraldein Mohammed Hamad; Yousif M ElhajAnemia is defined as a hemoglobin level of less than the 5th percentile for age. Causes vary by age. Most children with anemia are asymptomatic, and the condition is detected on screening laboratory evaluation. Screening is recommended only for high-risk children. Anemia is classified as microcytic, normocytic, or macrocytic, based on the mean corpuscular volume. Mild microcytic anemia may be treated presumptively with oral iron therapy in children six to 36 months of age who have risk factors for iron deficiency anemia. If the anemia is severe or is unresponsive to iron therapy, the patient should be evaluated for gastrointestinal blood loss. Other tests used in the evaluation of microcytic anemia include serum iron studies, lead levels, and hemoglobin electrophoresis. Normocytic anemia may be caused by chronic disease, hemolysis, or bone marrow disorders. Workup of normocytic anemia is based on bone marrow function as determined by the reticulocyte count. If the reticulocyte count is elevated, the patient should be evaluated for blood loss or hemolysis. A low reticulocyte count suggests aplasia or a bone marrow disorder. Common tests used in the evaluation of macrocytic anemias include vitamin B12 and folate levels, and thyroid function testing. A peripheral smear can provide additional information in patients with anemia of any morphologyItem Antibacterial activity of extract Acacia nilotica against known organisms (Escherich coli ,Pseudomonas aeruginosa ,Staphylococcus aureus ) in El sheikh Abdullah El badri University during may march July 2018.(جامعة الشيخ عبدالله البدري, 2018-01-01) Alrayan mohammed saeed; Kawther moutasim mohammed; Maab babiker mohammed; Nosiba awada lkareem; Nehad abdalla mohammed; Hajar Khalid eltayb; Hiba yousif osmaThis study tested the in vitro antibacterial activity of Acacia nilotica extract against know isolated bacteria (Escherichia coli, Pseudomonas aeruginosa ,Staphylococcus aureus ).The in vitro antimicrobial susceptibility testing was performed using disc diffusion test. The result showed that Acacia nilotica extract exhibited high antibacterial activity against known isolate organism The activity of Acacia nilotica extract was controlled with gentamycin اختبرت هذه الدراسة النشاط المضاد للبكتيريا في استخراج أكاسيا نيلوتيكا ضد البكتيريا (Staphylococcus aureus ,Pseudomonas aeruginosa ,Escherichia coli ) تم اختيار حساسية مضادات الميكروبات باستخدام طريقة نشر القرص وقد تم تحديد الحد الأدنى من تركيزات البكتيريا أوضحت النتائج أن مستخلصات أكاسيا نيولوتيكا أظهرت فعالية عالية ضد أنواع البكتيريا التي تم إستخدامها وقد تم التحكم في نشاط مستخلصات أكاسيا نيلوتيكا مع بعض المضادات الحيوية تشمل جنتاميسينItem Antibiotic Resistance: Overview(جامعة الشيخ عبدالله البدري, 2021) Mosab Nouraldein Mohammed HamadThe threat of antibiotic resistance weaken development in health care, food production, and life expectancy. It is estimated that, without an effective response, resistance to antimicrobial medicines might lead death of 19 persons/ every minute by 2050Item archaeopar asitology(جامعة الشيخ عبدالله البدري, 2018) Mosab Nouraldein Mohammed HamadArchaeoparasitology, a multi-disciplinary field within paleopathology, is the study of parasites in archaeological contexts. It includes studies of the protozoan and metazoan parasites of humans in the past, as well as parasites which may have affected past human societies, such as those infesting domesticated animals. Reinhard suggested that the term "archaeoparasitology" be applied to "... all parasitological remains excavated from archaeological contexts ... derived from human activity" and that "the term Paleoparasitology be applied to studies of nonhuman, paleontological material." Paleoparasitology includes all studies of ancient parasites outside of archaeological contexts, such as those found in amber and even dinosaur parasites. The first archaeoparasitology report described calcified eggs of Bilharzia haematobia (now Schistosoma haematobium) from the kidneys of an ancient Egyptian mummy. Since then, many fundamental archaeological questions have been answered by integrating our knowledge of the hosts, life cycles and basic biology of parasites, with the archaeological, anthropological and historical contexts in which they are found.Item Are Dioxins the Causative Agent of Polycystic Ovaries Syndrome?(جامعة الشيخ عبدالله البدري, 2022-02-21) Mosab Nouraldein Mohammed Hamad*Abstract Stein-Leventhal syndrome (Polycystic ovaries syndrome), represent one of the major obstacles facing reproductive medicine re searchers, because there is no information about the etiology of it, and that made them fail to draw smile on faces of millions of women around the world, who are suffering from it. Scientists said that it is attributed to genetic and environmental factors, and we hypothesized that it was caused by environmental pollution by dioxins (specifically heavy metals), which disturb aryl hydrocarbon receptor and that lead to disturbing of nuclear receptors and then express genes which lead to hormonal, metabolic and immunologi cal abnormalities appear in PCOS patients. And fortunately this hypothesis supports our hypothesis about the etiology of COVID-19 and its variants, clinically and epidemiologically. PCOS can be transmitted transmammary, sexually from Dixon exposed male part ners, and due to direct exposure to Dixon either via explosion or by excessive use of makeup. Experimental studies are required to test our hypothesis.Item Are Dioxins the Causative Agent of Polycystic Ovaries Syndrome?(جامعة الشيخ عبدالله البدري, 2022-02-21) Mosab Nouraldein Mohammed HamadAbstract Stein-Leventhal syndrome (Polycystic ovaries syndrome), represent one of the major obstacles facing reproductive medicine re searchers, because there is no information about the etiology of it, and that made them fail to draw smile on faces of millions of women around the world, who are suffering from it. Scientists said that it is attributed to genetic and environmental factors, and we hypothesized that it was caused by environmental pollution by dioxins (specifically heavy metals), which disturb aryl hydrocarbon receptor and that lead to disturbing of nuclear receptors and then express genes which lead to hormonal, metabolic and immunologi cal abnormalities appear in PCOS patients. And fortunately this hypothesis supports our hypothesis about the etiology of COVID-19 and its variants, clinically and epidemiologically. PCOS can be transmitted transmammary, sexually from Dixon exposed male part ners, and due to direct exposure to Dixon either via explosion or by excessive use of makeup. Experimental studies are required to test our hypothesisItem Are Dioxins the Causative Agent of Polycystic Ovaries Syndrome?(جامعة الشيخ عبدالله البدري, 2020) Mosab Nouraldein Mohammed HamadAbstract Stein-Leventhal syndrome (Polycystic ovaries syndrome) , represent one of the major obstacles facing reproductive medicine researchers , because there is no information about the etiology of it, and that made them fail to draw smile on faces of millions of women around the world, who are suffering from it. Scientists said that it is attributed to genetic and environmental factors , and we hypothesized that it was caused by environmental pollution by dioxins ( specifically heavy metals) , which disturb aryl hydrocarbon receptor and that lead to disturbing of nuclear receptors and then express genes which lead to hormonal , metabolic and immunological abnormalities appear in PCOS patients. And fortunately this hypothesis supports our hypothesis about the etiology of COVID-19 and its variants , clinically and epidemiologically. PCOS can be transmitted transmammry , sexually from Dixon exposed male partners , and due to direct exposure to Dixon either via explosion or by excessive use of makeup .Experimental studies are required to test our hypothesis.Item Artifacts(جامعة الشيخ عبدالله البدري, 2018) Mosab Nouraldein Mohammed HamadAnything in a specimen which is caused by the technique used and doesn't reflect the original specimenItem Ascaris lumbricoides(جامعة الشيخ عبدالله البدري, 2018) Mosab Nouraldein Mohammed HamadAscaris lumbricoides is the largest nematodes parasitizing the human intestine . The name derived from Askaris means intestinal worm and lubricus means resembling with common earth worm .