Antigiardial Activity and Toxicological Exploration of Cannabis Sativa Extracts
| dc.contributor.author | Elbadri E. Osman | |
| dc.date.accessioned | 2023-12-21T09:55:05Z | |
| dc.date.available | 2023-12-21T09:55:05Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Abstract— The present study has been attempt to elucidate antigiardial activity and explore the cytoxicity, investigation on liver Diagnostic Enzymes and Changes in serum constituents of Cannabis Sativa aerial parts and seeds, which were extracted by Petroleum ether and methanol. Aerial parts methanolic extract gave 63.6% mortality after 72 hours at concentration 1000 ppm (IC50 0.13 ppm) comparing with metrondizole (IC50 0.0125 ppm). While the other extracts found inactive as antigiardiasis after 72 hours. The slight increase in Aspartate amino transferase (AST), Alanine amino transferase (ALT) and Alkaline phosphatase (ALP) liver enzyme and total protein, urea, albumin and calcium which indicate some degree hepatic nefropathy effect of such plant petroleum ether extract. Moreover, phytochemical examination was carried out firstly and revealed that, the petroleum ether extract of Cannabis sativa seed do not contain tetrahydrocannbinol (THC), cannabinol (CBN) and cannabidaiol (CBD). However, all extracts showed no significant cytotoxic activity against vero cell line. Index Terms— Giardia lamblia, Cytotoxicity, Cannabis sativa, Liver enzymes | |
| dc.identifier.uri | https://ds.eaeu.edu.sd/handle/10.58971/906 | |
| dc.language.iso | other | |
| dc.publisher | جامعة الشيخ عبدالله البدري | |
| dc.title | Antigiardial Activity and Toxicological Exploration of Cannabis Sativa Extracts |