Browsing by Author "Mohammed Osman Ali"

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    Assessment of Fibrinogen Level and Platelets Parameters among Vaccinated Healthy Individuals with COVID-19 Vaccine at Shendi Town
    (جامعة الشيخ عبدالله البدري, 2022-06-10) Eslam Abdalla Mohammed Ahmed; Mohammed Osman Ali; Lana Jamal Abubaker; Ghanem Mohammed Mahjaf; Hamza Ahmed Hassan; Mosab Nouraldein Mohammed Hamad
    Abstract: Background: Covid-19 vaccine is an immunization method used to reduce coronavirus incidence but lately caused life-threatening events such as thrombosis with thrombocytopenia syndrome. Methods: This is a case control study conducted at Shendi town to evaluate platelet parameters and fibrinogen levels in vaccinated healthy individuals With Covid-19 vaccines between Augusts to November 2021. A total of (100) vaccinated healthy individual With the Covid-19 vaccine was enrolled in the study as test groups, compared with (50) healthy volunteers as a control group. Venous blood samples were transferred into Trisodium citrate and EDTA anticoagulant. Data was collected using a questionnaire and the (SPSS) version (22) program was used for data analysis. Results: The study revealed that the vaccinated healthy individuals were; (50%) male and (50%) female. The platelets parameter and fibrinogen indicated the mean values of platelets count, mean platelets volume, platelets distribution width, platelet crit, and fibrinogen, in Janssen vaccine groups, were (251.14 109\L), (8.39 fl), (15.6), (0.203%), and (158 mg\dl) respectively. The results study revealed the mean of PLT, MPV, PDW, PCT, and Fibrinogen, in Astrazeneca vaccine groups, were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg/dl) respectively. Also explained the mean of PLT, MPV, PDW, PCT and Fibrinogen, in Astrazeneca vaccine groups were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg\dl) respectively and in Janssen vaccine groups the mean values of PLT, MPV, PDW, PCT, Fibrinogen were ( 251.14 109\L), (8.39fl), (15.63), (0.2034%), (158 mg\dl) respectively. Conclusions: Covid-19 vaccines are responsible for significant changes in fibrinogen level in both AstraZeneca and Janssen vaccine groups.
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    Evaluation of Prothrombin Time Activated Partial Thrombo- plastin Time and Fibrinogen Level in Diabetic Pregnant Women in Shendi Town, Sudan
    (جامعة الشيخ عبدالله البدري, 2023-09-01) Mosab Nouraldein Mohammed Hamad; Alsayed Nouh M. Aldoush; Mohammed Osman Ali; Rahma Abdo Ahmed Osman; ,Tibyan Abd Almajed Altaher; Ghanem Mohammed Mahjaf; Ammar abdelmola5
    Abstract Background: Pregnancy is a unique physiological event that might have an impact on a woman›s coagulation and fibrinolytic system. Pregnant women and fetuses may be at risk for thrombotic and bleeding problems due to an abnormally hypercoagulable state during diabetic pregnancy. Thus, pregnant women must have regular coagulation tests to keep track of their coagulation and fibrinolytic systems. Objective: This research was carried out to analyze Prothrombin Time, Activated Partial Thromboplastin Time, and fibrinogen level in diabetic pregnant and normal pregnant women in Shendi town in Almak Nemer hospital during the period from June to November 2021. Materials and Methods: In tri-sodium citrate, 150 venous blood samples total were taken, 100 from diabetic pregnant women as cases and 50 from healthy pregnant women as controls. A questionnaire was employed to gather certain patient-related data. Coagulometer tests were performed on blood samples. Results: It was found that pregnant women with diabetes had a significant increase in PT and APTT but a minor increase in fibrinogen when compared to the control result. PT and PTT values were insignificant increase with age, number of pregnancies, and thestage of pregnancy. Conclusions: In diabetic pregnant women, alterations in the levels of coagulation markers were seen. And the coagulation parameter ranges were reported, which can serve as a point of reference for medical professionals to more precisely monitor the coagulation and fibrinolytic system in pregnant diabetic patients.
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    valuation of Prothrombin Time Activated Partial Thrombo plastin Time and Fibrinogen Level in Diabetic Pregnant Women in Shendi Town, Sudan
    (جامعة الشيخ عبدالله البدري, 2023-09-01) Mosab Nouraldein Mohammed Hamad; Alsayed Nouh M. Aldoush; Mohammed Osman Ali; Rahma Abdo Ahmed Osman; Tibyan Abd Almajed Altaher; Ghanem Mohammed Mahjaf; mmar abdelmola
    Abstract Background: Pregnancy is a unique physiological event that might have an impact on a woman›s coagulation and fibrinolytic system. Pregnant women and fetuses may be at risk for thrombotic and bleeding problems due to an abnormally hypercoagulable state during diabetic pregnancy. Thus, pregnant women must have regular coagulation tests to keep track of their coagulation and fibrinolytic systems. Objective: This research was carried out to analyze Prothrombin Time, Activated Partial Thromboplastin Time, and fibrinogen level in diabetic pregnant and normal pregnant women in Shendi town in Almak Nemer hospital during the period from June to November 2021. Materials and Methods: In tri-sodium citrate, 150 venous blood samples total were taken, 100 from diabetic pregnant women as cases and 50 from healthy pregnant women as controls. A questionnaire was employed to gather certain patient-related data. Coagulometer tests were performed on blood samples. Results: It was found that pregnant women with diabetes had a significant increase in PT and APTT but a minor increase in fibrinogen when compared to the control result. PT and PTT values were insignificant increase with age, number of pregnancies, and thestage of pregnancy. Conclusions: In diabetic pregnant women, alterations in the levels of coagulation markers were seen. And the coagulation parameter ranges were reported, which can serve as a point of reference for medical professionals to more precisely monitor the coagulation and fibrinolytic system in pregnant diabetic patients.