Antigiardial, Amoebicidal and Cytotoxic activity of the plant Prosopis juliflora leave extracts

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dc.contributor.authorElbadri E. Osman
dc.date.accessioned2023-12-21T10:00:22Z
dc.date.available2023-12-21T10:00:22Z
dc.date.issued2014
dc.description.abstracthe present study was carried out to evaluate antigiardial, amoebicidal activity and explore the cytotoxicity of Prosopis juliflora (Leaves) Variety supreme court Leaves petroleum ether and methanolic extracts in vitro. Tested were performed using four concentrations: (1000 ppm, 500 ppm, 250 ppm and 125 ppm). The highest activity against Giardia lamblia, with respect to time, was obtained from petroleum ether extract which exhibited 78.91% mortality within 72 h with a concentration of 500 ppm followed by the methanolic extract which exhibited 77.48% mortality within 72 h with a concentration of 1000 ppm. On the other hand the lowest antigiardial activity was recorded by petroleum ether extract 38.55 % mortality with 1000 ppm concentration in 24 hours. The highest activity against Entamoba histolytica, with respect to time, was obtained from methanolic extract which exhibited 71.97% mortality within 72 h with a concentration of 1000 ppm. On the other hand the lowest antiamobic activity was recorded by petroleum ether extract 31.88% mortality with 125 ppm concentration within 24 hours. The cytotoxicity of methanol and petroleum ether extract had varying degrees of toxicity to vero cell lines with IC50 731.79 µg/ml for the methanol extract and 11.22 µg/ml for the petroleum ether extract.
dc.identifier.urihttps://ds.eaeu.edu.sd/handle/10.58971/909
dc.language.isoother
dc.publisherجامعة الشيخ عبدالله البدري
dc.titleAntigiardial, Amoebicidal and Cytotoxic activity of the plant Prosopis juliflora leave extracts
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