Molluscicidal Activity of Acacia seyal (Dell) Bark Methanolic Extract Against Biomphalaria pfeifferi Snails
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Date
2016
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جامعة الشيخ عبدالله البدري
Abstract
The Acacia seyal Dell family Mimosaceaeis is known locally as Talha tree. Many medicinal uses such as treatment
of dysentery, leprosy, colds, diarrhea, hemorrhage, ophthalmic, intestinal ailments, rheumatic pains, colds and
fevers, have been attributed to this tree. Schistosomiasis, a water-borne parasitic disease caused by Schistosome(s)
a genus of digenetic trematode worms, infects man and animals in tropical and sub tropical regions. It is the second
most prevalent parasitic disease in the world ranked only after malaria regarding the number of people infected
and those at risk. More than 90% of the cases are occurring in Africa. The purpose of this study was to investigate
the molluscicidal activiat ty of Acacia seyal bark methanolic extract against the snail Biomphlaria pfeiffer.
Different concentrations (1000, 500, 250, 125, 62.5, 31.25, 15.625, 7.8125 and 3.91 ppm) of the Acacia seyal bark
methanolic extract, were investigated in vitro against snail Biomphlaria Pfeiffer. A. seyal bark methanolic extract
exhibited 100% mortality within 24 h, only at a concentration of 1000 ppm; and exhibited 100% mortality within
48 h, at 1000, 500, 250, 125 and 62.5 ppm. The IC50 of bark of A. seyal at 24 h and 48 h was 80.79 and 34.33
ppm, respectively. These findings prove the potent in vitro activity of A. seyal (bark) methanolic extract against
Biomphlaria pfeiffer