MOA Duplication & Deletion Theory: COVID-19 Pathogenesis Mechanism: Gene Duplication, Retrotransposition, 4p15.1-pter Duplication and a 4q35.1-qter Deletion in a Recombinant of Chromosome 4 Pericentric Inversion
| dc.contributor.author | Mosab Nouraldein Mohammed Hamad | |
| dc.date.accessioned | 2023-11-23T09:34:57Z | |
| dc.date.available | 2023-11-23T09:34:57Z | |
| dc.date.issued | 2020-04-22 | |
| dc.description.abstract | Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It is affecting 213 countries and territories around the world. The disease causes respiratory illness (like the flu) with symptoms such as a cough, fever, and in more severe cases, difficulty breathing, cardiac problems were also observed in many COVID-19 patients.We theorize that COVID-19 induce mutation in chromosome 4 lead to 4p15.1-pter Duplication and a 4q35.1-qter Deletion , and the neurological and cardiac disorders observed among infected persons resulted from retrotransposition mechanism of gene duplication occur in the specified region of chromosome 4 mentioned above. Genetic studies to chromosome 4 of COVID -19 patients recommended to confirm MOA duplication and deletion theory (4p15.1-pter Duplication and a 4q35.1-qter Deletion). | |
| dc.identifier.uri | https://ds.eaeu.edu.sd/handle/10.58971/437 | |
| dc.language.iso | other | |
| dc.publisher | جامعة الشيخ عبدالله البدري | |
| dc.title | MOA Duplication & Deletion Theory: COVID-19 Pathogenesis Mechanism: Gene Duplication, Retrotransposition, 4p15.1-pter Duplication and a 4q35.1-qter Deletion in a Recombinant of Chromosome 4 Pericentric Inversion |
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