Seroprevalence of Treponema Palladium Infection among Blood Donors in Darfur Region, Western Sudan 201

ABSTRACT Background: Treponema palladium (T.P) is a pathogenic bacteria induces syphilis, a systemic disease spread by sexual contact, blood transfusions. Objective: To recognize Treponema palladium seropositive blood donors and to explore the association between syphilis serological evidence and age as well as demographic information. Methods: In Darfur, Western Sudan, a retrospective analysis of sequential blood donation results from January to December 2017 was conducted. Percentages were used to measure the descriptive numbers. The p-value was used to assess the statistical significance of the measure, and the Chi-square was used to test trends. Results: A total of 4527 people volunteered to donate blood. They were all men between the ages of 17 and 49. A total of 493 (10.9 %) donors tested positive for syphilis, while 4034 (89.1 %) tested negative. study showed insignificant correlation between residence and serological evidence of syphilis (P = 0.23). Age was shown to be a strong indicator of transfusion-transmissible infections (P = 0.02). As compared to the other age classes, the frequency of (21-25) and (26-30) years was higher (51/428) 10.6% and (141/971) 12.7 %, respectively. Conclusions: In North Darfur, a high prevalence of Treponema palladium infection has been documented among blood donors. There was no statistically significant association between syphilis and occupancy, although there was a strong prevalence in a particular age demographic with a statistically significant correlation.