ABO and Rhesus Grouping among Sudanese Patients with Coronary Artery Disease at Sudan Heart Center-Khartoum State

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2019
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جامعة الشيخ عبدالله البدري
Abstract
Abstract Background: Many reports have appeared in recent years suggesting an association between blood groups and various manifesta tions of heart diseases. Many risk factors have been suggested as risk factors for Coronary Heart Disease. Among them is the ABO blood grouping. Materials and Methods: This a descriptive analytical study aimed to determine the frequency of blood group and Rhesus factor of patients with cardiovascular diseases at Khartoum state, during the period from October 2018 to March 2019. Five hundred patients with coronary artery diseases attended Sudan center of Heart and 500 apparently healthy controls were enrolled in this study. An informed consent was obtained from each participant before blood sample collection. ABO and Rh factor were performed by slide techniques using specific anti-sera. Thereafter, data was analyzed and organized by Microsoft Excel and SPSS computer program. Results: The results showed that most common blood group in patients with coronary artery diseases was O followed by A, and then B and least frequent was AB. Majority of patients with coronary artery diseases were Rh positive. Most common blood group was O (44.2%) followed by A (30.4%) and then B (21.4%) and least frequent was AB (4%). Finally, the results of the present study showed that there is no association of ABO blood group and Rh factor with cardiovascular diseases. Although the frequent of coronary artery diseases was higher in O group, the difference was statistically insignificant. We noticed that there’s an association between Coronary heart disease and ABO blood group due to the result of the P value (0.0003). Conclusion: We concluded that the risk of Coronary heart disease for individuals with non O blood grouping is higher than that of people with O blood grouping. And no association of Rhesus factors with Coronary Heart disease.
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