Synthesis and antibacterial activity of 3-nitrobenzaldehyde semicarbazone ligand and its Ni (II) and Cu (II) Complexes
No Thumbnail Available
Date
2020-09-28
Journal Title
Journal ISSN
Volume Title
Publisher
جامعة الشيخ عبدالله البدري
Abstract
Abstract
Schiff bases are the most widely used organic compounds. They have been shown to
exhibit a broad range of biological activities, including; antifungal, antibacterial, anti malarial, anti-proliferative, anti-inflammatory, antiviral, and antipyretic properties. In
this study semicarbazone ligand was prepared by condensing 3-nitropenzaldehyde with
semicarbazide hydrochloride in 1:1 molar ratio in ethanolic medium. This ligand was used
to synthesize metal complexes of copper (II) and nickel (II) in 1:2 molar ratio using ethanol
as a solvent .Characterization and structure elucidation of prepared metal complexes have
been investigated on the basis of molar conductance and UV and IR spectral studies. The
all prepared compounds showed a vital effect against both types of bacteria gram positive
(Staphylococcus-aurous) and gram negative (Escherichia-coli).