The Impact of Oxidative Stress on Male Infertility
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Date
2023-03
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Publisher
جامعة الشيخ عبدالله البدري
Abstract
Abstract:
Reactive oxygen species, also known as oxygen and oxygen-derived
oxidants, cause cellular damage at a higher rate under the term "oxidative
stress" (ROS). Oxidative stress is typically present as a background factor
in all live aerobic cells. This oxidative process can be accelerated and
lead to cell damage by several stress-related situations, including chronic
disease states, aging, toxin exposure, physical injury, and exposure to a
variety of foods. One of the main contributing factors to infertility is
thought to be the malefactor. A new and significant reason, oxidative
stress, has been discovered in addition to the traditional causes of male
infertility, such as varicocele, cryptorchidism, infections, obstructive
lesions, cystic fibrosis, trauma, and tumors. Reactive oxygen species
(ROS) and antioxidants in the body are out of balance, which leads to
oxidative stress. This potent mechanism can cause damage, deform, and
ultimately result in male sterility in sperm. The physiological significance
of ROS, their function in healthy sperm function, and the
pathophysiology of ROS in the male reproductive system are all covered
in this article.