Cytological Changes in Buccal Mucosa among Glue Abusers in Shendi, Sudan
No Thumbnail Available
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
جامعة الشيخ عبدالله البدري
Abstract
Abstract
Background: Glue sniffing among young people on the streets has gone completely out of control. The majority of
street kids start out sniffing glue before moving on to other, more extreme narcotics. The organizations tackling the
drug problem claim that because it is inexpensive and widely accessible, the majority of young people on the streets
smell it.
Objective: The purpose of this study was to assess how sniffing glue affected the buccal mucosal cells.
Materials and Methods: This cross-sectional descriptive study was carried out at Shendi town between March
2021 and March 2022. The study involved 150 participants under the age of 25, of whom 50 were glue abusers. The
remaining 50 participants served as the (control1) group, and their parameters were similar to those of the abusers',
with the exception that they did not abuse glue. The final 50 participants served as the (control 2) group, and they
appeared to be in good health and did not use tobacco, Glue sniffing, or another type of addiction. Buccal samples
were taken from each group, strained by pap stain, and microscopically examined. A standardized face-to-face
questionnaire was utilized to gather data, and the (SPSS) version (11.5) application was used to analyze the results.
Results: The study revealed a significant P-value of nuclear atypia among study populations, inflammation, and
infection was 0.000, the significant relationship of nuclear atypia with the duration of glue snuffing and dose of glue
with P-value 0.000,0.001 respectively.
Conclusions: The usage of glue caused considerable morphological alterations in mucosal cells, such as nuclear
atypia and pre-nuclear hallo, as well as inflammations and infections (bacterial and viral)