Browsing by Author "Nazzla Abd Alhameed H. Mohammed1"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Detection of secretor gene among Sudanese patients with chronic renal failure in Shendi town: A cross sectional study
    (جامعة الشيخ عبدالله البدري, 2023) Nazzla Abd Alhameed H. Mohammed1; Elfatih Mohammed A. Ali1,; Alaa Babiker H. Alkab1; Ghanem Mohammed Mahjaf2; Tibyan Abdalmajed Altaher3; Mosab Nouraldein Mohammed Hamad4*
    Abstract: Background: Secretor status is valuable with some diseases in clinical and forensic medicine. Objectives: This study aimed to evaluate the status of secretors and non-secretors in chronic renal failure patients under hemodialysis in Shendi town at the kidney treatment and surgery center (Sudan). Method: Saliva samples were collected from fifty patients (58% were male) aged from 15 to 65 years and secretor status was studied by the hemagglutination inhibition method of saliva. Result: results showed that 68% of the study population were non-secretors. probable frequency of the Se and se genes was 17,6% and 82,4% while the frequency of SeSe, Sese, and sese allele genes was 3%, 29%, and 68% respectively. were calculated by utilizing Hardy-Weinberg Theorem for probabilities and possibilities. Frequencies of the non-secretor status among various ABO blood groups were 63.2% in group A, 75% in group B, and 72.7% in group O. Conclusion: We conclude that non-secretors are more prevalent in chronic renal failure. In the present study observed that non-secretors were more common as compared to secretors, non-secretors are more prone to renal failure.