Browsing by Author "Hamza Ahmed Hassan"
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Item Assessment of Fibrinogen Level and Platelets Parameters among Vaccinated Healthy Individuals with COVID-19 Vaccine at Shendi Town(جامعة الشيخ عبدالله البدري, 2022-06-10) Eslam Abdalla Mohammed Ahmed; Mohammed Osman Ali; Lana Jamal Abubaker; Ghanem Mohammed Mahjaf; Hamza Ahmed Hassan; Mosab Nouraldein Mohammed HamadAbstract: Background: Covid-19 vaccine is an immunization method used to reduce coronavirus incidence but lately caused life-threatening events such as thrombosis with thrombocytopenia syndrome. Methods: This is a case control study conducted at Shendi town to evaluate platelet parameters and fibrinogen levels in vaccinated healthy individuals With Covid-19 vaccines between Augusts to November 2021. A total of (100) vaccinated healthy individual With the Covid-19 vaccine was enrolled in the study as test groups, compared with (50) healthy volunteers as a control group. Venous blood samples were transferred into Trisodium citrate and EDTA anticoagulant. Data was collected using a questionnaire and the (SPSS) version (22) program was used for data analysis. Results: The study revealed that the vaccinated healthy individuals were; (50%) male and (50%) female. The platelets parameter and fibrinogen indicated the mean values of platelets count, mean platelets volume, platelets distribution width, platelet crit, and fibrinogen, in Janssen vaccine groups, were (251.14 109\L), (8.39 fl), (15.6), (0.203%), and (158 mg\dl) respectively. The results study revealed the mean of PLT, MPV, PDW, PCT, and Fibrinogen, in Astrazeneca vaccine groups, were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg/dl) respectively. Also explained the mean of PLT, MPV, PDW, PCT and Fibrinogen, in Astrazeneca vaccine groups were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg\dl) respectively and in Janssen vaccine groups the mean values of PLT, MPV, PDW, PCT, Fibrinogen were ( 251.14 109\L), (8.39fl), (15.63), (0.2034%), (158 mg\dl) respectively. Conclusions: Covid-19 vaccines are responsible for significant changes in fibrinogen level in both AstraZeneca and Janssen vaccine groups.Item Assessment of Iron Profile among Sudanese Patients with Chronic Renal Failure in Shendi Town(2022) Elham Mansour E Mohammed; Hamza Ahmed Hassan; Ghanem Mohammed Mahjaf; Tibyan Abd Almajed Altaher; Mosab Nouraldein Mohammed HamadAbstract: This is a descriptive cross-sectional case-control study conducted in Al-Mak Nemir University Hospital in Shendi town to evaluate the iron profile in patients with chronic renal failure during the period March to July 2018. The study included thirty patients who were diagnosed with chronic renal failure and the study group was compared with ten healthy volunteers as a control group. Blood samples were collected from the two groups, Iron profile parameters were measured, Data was collected using a structured face-to-face questionnaire, and the (SPSS) version (11.5) program was used for data analysis. The study revealed the patients with chronic renal failure were (73.3%) male and (26.6%) female, distributed as (66.7%) have (31-50) years old, (23.3%) have (51-70) years old, and (10%) have (71-100) years old. The iron profile indicated that the mean values of S. iron, S. ferritin, and TIBC, were (182.2667ug/dL), (267.4000ug/L), and (195.2333ug/dL) respectively. This study showed that chronic renal failure is responsible for significant changes in iron profile.Item Determination of Platelet Count and platelet Indices in Women after Normal Delivery in Shendi Town, Sudan(جامعة الشيخ عبدالله البدري, 2023) Areej Hussein FudulAlmoula; Tibyan Omer Alseer; Hamza Ahmed Hassan; TibyanAbd Almajed; Ghanem Mohammed Mahjaf; Mosab Nouraldein Mohammed HamadAbstract Background: Delivery is the process of birth. As the uterus contracts, the lower part stretches and thins, the cervix expands, the birth canal is formed, and the baby sinks through the pelvis, Platelet counts of less than 150,000 per cubic millimeter during uncomplicated pregnancies are described as gestational thrombocytopenia if no alternative cause is identified. Platelet counts may be even lower in women with pregnancy-related complications. Objective: The purpose of this study was to measure the platelet count and platelet index in women after normal delivery. Methods: This descriptive study was conducted in the city of Shendi during the period from March (2021) to January (2022) and measured the platelet count and platelet index in women after normal delivery. P.value of the test at the 95- confidence level was 0.000, less than 0.05, indicating significant variation between the case and control groups in platelet counts. Hundreds of venous blood samples were collected for use in this study, 50 of which were collected from the test group and 50 from the control group. Platelet counts and platelet indices (including platelet critical value (PCT), platelet distribution width (PDW), and mean platelet volume (MPV) were determined for all samples and performed in an automated manner using a hematology analyzer. Results: The study showed that the mean platelet count in the delivery group was 147.84 compared to 263.14 in the control group. The P. value was significant (P. value 0.000). The most affected age for platelet count in the study group was 30 years and older, with a platelet count percentage of 84%. The most effective number of workers for platelet counts in postpartum women was 2 or more workers. The platelet count percentage was 84%. The study showed that the mean platelet volume (MPV) for the delivery group was 8.696 compared to 8.616 for the control group. The value of the test was not significant (0.620). The mean platelet distribution width (PDW) was 15.750 for the treatment group and 15.828 for the control group. The P. value was not significant (0.418)Item Evaluation of Complete Blood Count and D. Dimer in Patients with COVID-19 Infection in Shendi Town(جامعة الشيخ عبدالله البدري, 2022-09-06) Hamza Ahmed Hassan; Elfatih Mohammed Abdalla Ali; Eltayeb Ahmed Motasim alnger; Eslam Abdalla M. Ahmed; Alaa Babiker H. Alkab; Ghanem Mohammed Mahjaf; Mosab Nouraldein Mohammed HamadAbstract: Background: Covid-19 can Cause Various Conditions Including respiratory, enteric, and neurological diseases, and led to a pandemic that has affected millions worldwide. Methods: This is a cross-sectional descriptive study conducted at Shendi teaching hospital which is located in Shendi town in Sudan to evaluate Haematological parameters and D. Dimer in patients with Covid-19 Infection in the period between May to September 2021. The study included (50) patients who were diagnosed with Covid-19 Infection and the study groups were compared with (50) healthy volunteers as a control group. 50 venous blood samples as case and 50 as control transferred into Tri sodium citrate and EDTA anticoagulant. Data was collected using a questionnaire and the (SPSS) version (22) program was used for data analysis. Results: The study revealed that the Covid-19 Infection patients were; (60%) males and (40) females. Complete blood count (CBC) indicated the mean values of Hb, PCV, RBCs, MCV, MCH, MCHC, in case group were (12.5 g/dl), (38.9%), (4.5x1012/l), (86.7 fl), (27.7 pg) and (32.0 g/dl) respectively. Also prevailed the mean of TWBCs, Neutrophil, lymphocyte, MID, Absolute Neutrophil, Absolute lymphocyte, Absolute MID, were (13.09x 109 /l), (79.27%), (11.79%), (8.77%), (10.38), (1.54), and (1.16) respectively. The study revealed the mean of platelet, D.dimer (296.63x 109 /l), (6.07ug/ml), respectively. Conclusions: Covid-19 Infection is responsible for significant changes in hemoglobin, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration, total white blood cells count differential and absolute neutrophils count and differential and absolute lymphocytes count and D. dimer.