Faculty of Medicine كلية الطب

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Browsing Faculty of Medicine كلية الطب by Author "Ghanem Mohammed Mahjaf"

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    Frequency of Red Blood Cells Sensitized with Allo-antibodies in cord blood in Atbara and Eldamer localities, Sudan
    (جامعة الشيخ عبدالله البدري, 2022-06-22) Mosab Nouraldein Mohammed Hamad; Nusaiba Mubarak Sirelkhatim Khalafalla; Elharam Ibrahim Abd Allah; Zakaria Albadawi Alagmi; Ghanem Mohammed Mahjaf
    Abstract: A direct antiglobulin test (DAT) is not routinely used in developing countries including Sudan. The direct antiglobulin test (DAT) is a screening test for antibodies present in an individual’s red cells and is used to diagnose hemolytic disease of the newborn (HDN). The study was to determine the prevalence of DAT among infants at Atbara and Eldamer. The study was designed as a descriptive, cross-sectional study carried out among neonates during January and February 2019 Atbara and Eldamer. ABO group and DAT were carried out among 100 samples of neonatal cord blood. Data were analyzed using SPSS version 22. A total of 100 neonates were recruited for the study. Among 100caces ABO incompatibility status was determined in 74 cases. The higher frequency was (O+, O+)(40%), the lower frequency was (AB+/AB+)(2%) while ABO incompatibility between neonates and mothers was found in 26 (26.0%) cases, The higher frequency of (A/O) incompatibility (15%), the lower frequency was (B+/A+),(AB+/A+)(1%) by the ABO group distribution at the Atbara & Eldamer localities. in this study positive DAT was detected in 2/100 (2.00%) cases (positive DAT was attributed to a typical antibody) two cases are the (O+/O+) group, These two neonates (O RhD positive) and the mothers (O RhD positive), The two cases of alloimmunization were mothers multipara without a history of past transfusions. The study concluded that sensitization with alloantibodies was found among neonatal blood which reflects the importance of detection of allo Abs among cord blood and mothers.