Waseem Sameer Kwami, Hamodi Ahmed SaeedMosab Nouraldein Mohammed Hamad2023-11-272023-11-272020-08-17https://ds.eaeu.edu.sd/handle/10.58971/532background: Natural antibacterial agents derived from different parts of medicinal plants (leaves, seeds, roots, flowers….etc) might represent an alternative treatment of infectious diseases, Plants with their wide variety of chemical constituents offer a promising source of new antimicrobial agents, with general as well as specific antibacterial activity. The aim of this study is to screen antibacterial activity of Moringa oleifera leaves and seeds extract against selected members of bacteria. Method: Five bacterial ATCC strains and seven clinically isolated strains were used in this study. 100 g of Moringa olifara leaves and 150 g of the coarsely powdered Seeds were extracted with 80 % methanol using soxhlet extractor apparatus for about eight hours. The antibacterial activity was determined by the agar well diffusion method .Muller Hinton agar medium was used for bacterial cultures. Results: The study reveals that the Moringa oleiferaleaves and seeds extract show prominent Invitro antibacterial activity against all used bacterial species and the antibacterial activity of leaves extract is stronger than antibacterial activity of seeds extract and these results showing the possibility of using this tree in treatment of diseases caused by these pathogens. Conclusion: The study concluded that the activity of this plant in the treatment of diseases associated with bacterial pathogens is validated and scientifically supported by the results obtained in this study.other