Mosab Nouraldein Mohammed Hamad2023-12-122023-12-1220170975-5888https://ds.eaeu.edu.sd/handle/10.58971/780Abstract- Background: Entamoeba coli is intestinal protozoan amoeba which is regarded tell now as commensal amoeba although their adverse symptoms that theymay cause in certain patients. Objectives: General Objectives: To know the phagocytic activity of Entamoeba coli against microorganisms. Specific Objectives: To know the phagocytic activity of Entamoeba coli against microorganisms that inhabit the intestinal tract. Methodology: The study based on data collected from previous studies. Result: Entamoeba coli phagocytosed bacterial flora of the gut, fungi of Sphaerita species and even Giardia lamblia trophozoites. Conclusion: Entamoeba coli is a potent phagocytic microorganism that engulf other microorganisms which may compete it in nutrients.other