Fania A. AlbadriMohamed Hashim FadellalaEptihal O. Rabh, Fatima S. Ahmad, Hadel S. MohamedNahed M. Abdallgader, Raga M. MostafaSafa S. MousaSara H. AlsiddigGhanem Mohammed MahjafMosab Nouraldein Mohammed Hamad2023-11-202023-11-202022-081858-943Xhttps://ds.eaeu.edu.sd/handle/10.58971/365Abstract: This is a cross-sectional study aimed to measure PTT and PT in pregnant women with the control group the study included Any well healthy pregnant women and exclusion any complicated pregnant women. in Atbara city in the period between March and July 2018. The study included 50pregnant women and 50 non pregnant as control. 2.5mlofcitrated blood was collected under ideal conditions and analyzed PT and APTT manually. The study proved after analyzing the results statistically by Statistical Package for social Sciences SPSS that found increased significance in PTT and PT when compare to control. we show the result of APTT was significantly increased and found the mean of APTT was 61.18(2.745) sec when compared to the control group found the mean of the control group was 39.82(2.745) sec and the result of PT was slightly increased, we found the mean of PT cases was 19.64(0.916) sec when compare to control found the mean of PT 18.90(0.584) sec. This study aims to assess the coagulation profile among pregnant women from the first to the third trimester to observe any change in coagulation profile PT, APTT.other