Determination of Bacteriological Profile of Antimicrobial Susceptibility Testing among Diabetic Patients with Urinary Tract Infections in Shendi, Sudan
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Date
2023-05-10
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جامعة الشيخ عبدالله البدري
Abstract
Abstract: Background: Urinary tract infection is a widespread microbial disease and 2nd most disease in women due to
the anatomy of women type 2 diabetes is a high risk of infection of the urinary tract. Objective: To identify the agent
that causes urinary tract infections in diabetic patients, select the best antibiotic, and assess the types of diabetes that are
connected with urinary tract infections. Materials and Methods: From May to August 2018, a hospital-based cross-
sectional study was carried out. According to the established methodology, urine samples were obtained for culture and
identification. All isolates underwent an antimicrobial susceptibility test (AST) using the Kirby-Bauer disk diffusion
method. The Statistical Package for the Social Science (SPSS) version 20 was used to import the data from Epi-data
version 3.2.1. Results: The study's findings indicated that E. coli is the most prevalent bacterium, with a prevalence of
approximately (30.2%). It is followed by K. pneumoniae (26.3%), and then by Staphylococcus aureus and Saprophiticus
in percentage (15%). Gentamicin has a high rate of antibiotic sensitivity (approximately 36%), while Ceftazidime has a
high rate of antibiotic resistance (about 35%). Around (52%) of people are resistant to Ceftriaxone and
Cloxacillin. Conclusions: There was a high rate of UTI in diabetes patients. Female diabetics were more likely to
experience UTIs than male diabetics.E. coli and K. pneumoniae species making up the majority of isolates. The isolated
pathogens were highly susceptible to Gentamicin, Cloxacillin, and Ceftriaxone. These findings demonstrate the
importance of glycemic management in diabetics for reducing UTIs, regardless of age or sex. By treating UTIs with the
appropriate antimicrobial medications and monitoring the antimicrobial susceptibility patterns of isolated
microorganisms, antibiotic-resistant urinary organisms can be managed.