Value of serum calcium in preeclamptic Sudanese women
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Date
2022-12-30
Journal Title
Journal ISSN
Volume Title
Publisher
جامعة الشيخ عبدالله البدري
Abstract
Abstract
Background: Preeclampsia is a pregnancy-related hypertensive disorder occurring in the
second half of the pregnancy and is one of the major causes of maternal and fetal morbidity
and mortality. Though the etiology is obscure, recent studies indicate that the levels of
serum calcium may play a role in the development of preeclampsia. The aim of this study to
find out the relationship of serum calcium in preeclamptic pregnancies compared to normal
pregnancies.
Methods: This was a case control study carried out at Bahari Hospital which included 100
women with preeclampsia in the third trimester of pregnancy as a study group and 100
healthy pregnant women in their third trimester of pregnancy as a control group with similar
maternal and gestational age. The concentration of the corrected total serum calcium was
measured by measuring total serum calcium and serum albumin using a spectrophotometric
method. Data was analyzed by using Statistical Package for Social Sciences (SPSS) version
23.
Results: The age of the participants was (18-45) years old, with gestational age ranging
from (34-36) weeks, there was no significant difference between the two groups in their
age, gestational age, with p value (0.5) and (0.2) respectively. Plasma calcium level was
lower in preeclamptic women as compared to healthy control subject, the mean value of
plasma calcium levels were (7.1±0.8) mg/dl and (9.6±0.4) mg/dl, in study and control
groups respectively, the difference in the mean were statistically significant with p value
(0.001).
Conclusion: Hypocalcaemia related to preeclampsia supports the hypothesis that
alternation in the total serum calcium levels may be involved in the possible pathogenesis
of preeclampsia.