Identification of Candida Species among Renal Transplanted Recipient, In Khartoum, Sudan 2021

No Thumbnail Available
Journal Title
Journal ISSN
Volume Title
جامعة الشيخ عبدالله البدري
bstract: Background: Kidney transplantation represents the optimal therapeutic tool for patients affected by end stage renal disease (ESRD), Candidiasis is a major challenge among renal transplant recipients (RTRs) worldwide and is associated with high morbidity and mortality rates. Fluconazole is the most commonly used agent for Candida infections Aim: to identify Candida spp from renal transplanted patients. Method: cross sectional study were done, 51 Urine sample was collected on sterile urine container then cultured on Sabouraud dextrose agar, incubated at 35 °C and observed daily for 7 days. When the growth of yeast colonies was observed, the Gram stain method was done to verify the absence of bacterial contamination. The yeasts were identified via germ tube test and chromogenic media to differentiate between candida spp. Results: out of 51 patients; female were more than male wit mean age group 45 years for both male and female.The cause of ESRD was; 19 (37.3%) had DM, 12(23.5%) had hypertension, 10(19.6%) had Glomerulonephritis and 3(5.9%) had kidney stone candida species among study group as follow; c.albicans isolated from 28 (54.9%) pt., c.glabrata isolated from 11 (21.6%) pt., c.tropicalis isolated from 6 (11.8%) pt., c.krusie isolated from 3 (5.9%) of pt. and 3(5.9%) had mixed infection. C.albicans, tropicalis and C.krusie had been distributed more among DM groups and less among kidney stone groups, on the other hand C.glabrata more isolated among Glomerulonephritis groups. There was no association between candida species and ESRD. Conclusion: There was no relation between candida spp and cause of ERDS.