Identification of Candida Species among Renal Transplanted Recipient, In Khartoum, Sudan 2021
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Date
2022-03-24
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جامعة الشيخ عبدالله البدري
Abstract
bstract: Background: Kidney transplantation represents the optimal therapeutic tool for patients affected by end stage renal disease (ESRD), Candidiasis is a major challenge among renal transplant recipients (RTRs) worldwide and
is associated with high morbidity and mortality rates. Fluconazole is the most commonly used agent for Candida
infections Aim: to identify Candida spp from renal transplanted patients. Method: cross sectional study were done, 51
Urine sample was collected on sterile urine container then cultured on Sabouraud dextrose agar, incubated at 35 °C and
observed daily for 7 days. When the growth of yeast colonies was observed, the Gram stain method was done to verify
the absence of bacterial contamination. The yeasts were identified via germ tube test and chromogenic media to
differentiate between candida spp. Results: out of 51 patients; female were more than male wit mean age group 45 years
for both male and female.The cause of ESRD was; 19 (37.3%) had DM, 12(23.5%) had hypertension, 10(19.6%) had
Glomerulonephritis and 3(5.9%) had kidney stone candida species among study group as follow; c.albicans isolated
from 28 (54.9%) pt., c.glabrata isolated from 11 (21.6%) pt., c.tropicalis isolated from 6 (11.8%) pt., c.krusie isolated
from 3 (5.9%) of pt. and 3(5.9%) had mixed infection. C.albicans, tropicalis and C.krusie had been distributed more
among DM groups and less among kidney stone groups, on the other hand C.glabrata more isolated among
Glomerulonephritis groups. There was no association between candida species and ESRD. Conclusion: There was no
relation between candida spp and cause of ERDS.