Browsing by Author "Mona A M Mageed2"

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    Keywords: Ringing Mobile phone, ECG heart rate, rhythm, chest pocket level, healthy adult. Abbreviations: ECG Electrocardiogram, HR Heart Rate
    (جامعة الشيخ عبدالله البدري, 2019) Esraa E K Abdurrahman1*; Mona A M Mageed2
    Abstract Faidherbia albida Dell. (Mimosodceae), locally known as alharaz. All plant parts have an important role in traditional medicine except for the root part. The study aims to quantify the alkaloids in the Faidherbia albida root chloroform extract and to assess the antifungal activity of the roots chloroform extract against three pathogenic fungi: Aspergillus fusarium, Aspergillus fulvus, and Candida albicans. The primary phytochemical analysis of chloroform extract showed the presence of alkaloids, diterpenes and flavonoids, Saponins and phytosterols, but glycosides were not detected. The yield percentage of the raw maceration extract is 3.8%. In thin-layer chromatography (TLC), it revealed the detection of one compound under U V light as light blue spots (RF 0.833). The total alkaloid content in the chloroform roots extract was 121.142mg AE/g, while the total phenol content is 53.960mg GAE/g. The extract at concentration 200mg/ml revealed no inhibition effect against all microorganisms tested except Candida albicans (17mm). This study found that Faidherbia albida contains a high concentration of alkaloids compared with the other plant parts and moderate phenol content compared with the leaves part, as well as anticandidal activity against both the standard and isolated strain tested.
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    Photochemical Analysis, Antioxidant Activity and Cytotoxicity of Adansonia digitata L. Seeds Ethanol Extract
    (جامعة الشيخ عبدالله البدري, 2019) Huiam Salah Eldeen IzzEldeen AbdAlaziz 1; Mona A M Mageed2
    Abstract Adansonia digitate Linn (Malvaceae) is a native plant to the west Sudan, locally named Tabaldy. Adansonia digitate seeds are believed to have nutritional and medicinal benefits in Sudan. The aims of this study are to screening the phytochemicals of Adansonia digitate L seeds ethanol extract and to assess the antioxidant activity and cytotoxicity. The phytochemical screening revealed the presence of glycosides, saponins, steroids, flavonoids, and protein, but alkaloids, tannins and resins were not detected. The antioxidant test of baobab seeds ethanol extract was performed by using the DPPH scavenging test which revealed a moderate activity (53.04±0.067) with IC50 value 0.092± 0.006. The cytotoxicity was tested using three cancer cell line: lung cancer cell (A549), breast cancer cell (MCF7), hepatic cancer cell (HEPG2) and tow normal cell line melanocytes cell (HFB4) and fibrinocytes cell (BHK). The cytotoxicity result of the seed aqueous ethanol extract was exhibited a cytotoxic effect against the normal cell tested (HFB4), (BHK) with IC50 11.6, and 24.5 µg/ml respectively and no effect on cancer cell tested except (MCF7) cell with IC50 11.5 µg/ml. This study does not support the use of seeds powder as nutrition due to the cytotoxic effect