Browsing by Author "Lana Jamal Abubaker"
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Item Assessment of Fibrinogen Level and Platelets Parameters among Vaccinated Healthy Individuals with COVID-19 Vaccine at Shendi Town(جامعة الشيخ عبدالله البدري, 2022-06-10) Eslam Abdalla Mohammed Ahmed; Mohammed Osman Ali; Lana Jamal Abubaker; Ghanem Mohammed Mahjaf; Hamza Ahmed Hassan; Mosab Nouraldein Mohammed HamadAbstract: Background: Covid-19 vaccine is an immunization method used to reduce coronavirus incidence but lately caused life-threatening events such as thrombosis with thrombocytopenia syndrome. Methods: This is a case control study conducted at Shendi town to evaluate platelet parameters and fibrinogen levels in vaccinated healthy individuals With Covid-19 vaccines between Augusts to November 2021. A total of (100) vaccinated healthy individual With the Covid-19 vaccine was enrolled in the study as test groups, compared with (50) healthy volunteers as a control group. Venous blood samples were transferred into Trisodium citrate and EDTA anticoagulant. Data was collected using a questionnaire and the (SPSS) version (22) program was used for data analysis. Results: The study revealed that the vaccinated healthy individuals were; (50%) male and (50%) female. The platelets parameter and fibrinogen indicated the mean values of platelets count, mean platelets volume, platelets distribution width, platelet crit, and fibrinogen, in Janssen vaccine groups, were (251.14 109\L), (8.39 fl), (15.6), (0.203%), and (158 mg\dl) respectively. The results study revealed the mean of PLT, MPV, PDW, PCT, and Fibrinogen, in Astrazeneca vaccine groups, were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg/dl) respectively. Also explained the mean of PLT, MPV, PDW, PCT and Fibrinogen, in Astrazeneca vaccine groups were (272.08 109\L), (8.13fl), (15.56), (0.2211%), (159 mg\dl) respectively and in Janssen vaccine groups the mean values of PLT, MPV, PDW, PCT, Fibrinogen were ( 251.14 109\L), (8.39fl), (15.63), (0.2034%), (158 mg\dl) respectively. Conclusions: Covid-19 vaccines are responsible for significant changes in fibrinogen level in both AstraZeneca and Janssen vaccine groups.Item Identification of Pathogenic Bacteria Isolated from Fingernails of Children in Shendi Locality(جامعة الشيخ عبدالله البدري, 2022-03-09) Lana Jamal Abubaker; Mosab Nouraldein Mohammed Hamad; Tarig Mohamed Ahmed Mohamed; Khalid S Hammad1; Ghanem M Mahjaf; Leila M AbdelgadeirAbstract Background: Recently a lot of studies focused on the global occurrence of resistant bacteria carriages. Fingernails are a perfect area for harboring bacteria. Children are the most age categories who harbor pathogenic bacteria in their fingernails. Objective: This was a prospective cross-sectional descriptive study aimed to identify the pathogenic bacteria isolated from the fin gernails of children in the Shendi locality; it also studied their antimicrobial susceptibility patterns. Methodology: The study included (70) participants, 37 (53%) males, and 33 (47%) females, within the age group (1- 10) years. Nails were collected and firstly cultured on nutrient broth then on blood agar and MacConkey incubated aerobically at 37c° for 24 hours. Isolated organisms were identified according to their colonial morphology, indirect gram staining reaction, biochemical tests, and antimicrobial susceptibility tests were done by the disc diffusion method. Result: The study revealed that 61 (87%) of children showed bacterial growth from fingernails. The isolated bacteria were Staphy lococcus aureus18 (29.1%), Bacillus spp 11 (17.7%), Escherichia coli 2 (3.2%), Klebsiella spp12 (19.3%), Enterobacter spp8 (13%), Citrobacter spp6 (9.6%), Proteus vulgaris4(6.5%) and Salmonella spp1 (1.6%). Ciprofloxacin 58 (93.5%) and Gentamicin40 (64.5 %) were the most effective antibiotics against the isolated bacteria in contrast they were mostly resistant to Nitrofurantoin 53 (85.5%), Amoxiclav 45(72.6%) and Doxycycline 39 (63%). Conclusion: Long nails and playing behaviors of children were the main factors for harboring bacteria in fingernails. Staphylococcus aureus was the most isolated bacteria while Ciprofloxacin was the most effective antimicrobial agent used.