Browsing by Author ", Sufian Khalid M. Noor"
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Item Medicinal Plants Explain the Significant Role of Uric Acid for Malaria Parasite(جامعة الشيخ عبدالله البدري, 2021-12-13) Mosab Nouraldein Mohammed Hamad; , Sufian Khalid M. Noor; Awadalla H Kashif; , Mohammed Medani Eltayeb; Abdelgadir Elamin Eltom; , Praveen Kumar Kandakurti; , Elizabeth Popova; Shafie Abdulkadir Hassan; , Yassin Bakri Salih; , Tarig Mohammed Elfaki; d Mohammed Ahmed Ibrahim AhmedMedicinal plants, recognized and employed in conventional medicine practices since prehistoric era. Plants produce thousands of chemical substances for functions counting defence against insects, fungi, bacterial and parasitic diseases. Malaria is most widespread parasitic infection , it caused by coccidian protozoa of the genus plasmodium , four species are mostly infect human, P. falciparum, P. vivax, P. malriae and P. ovale, Majority of malaria cases resulted from P. falciparum and P. vivax. Uric acid regarded as one of the damaging molecular patterns of malaria parasite infection, and in this review we discussed the potential role of medicinal plants used as antimalarial to diminish the level of uric acid in gout patients. These may suggest that most of the complication associated with malaria, may attributed to amplified level of uric acid . Experimental studies recommended.Item The Role of Aryl Hydrocarbon Receptor in Malaria Immunity during Adulthood, Childhood and Pregnancy: A Review(جامعة الشيخ عبدالله البدري, 2021-12-28) Mosab Nouraldein Mohammed Hamad; , Bader Saud Alotaibi; Rania Saad Abdulgader; , Sufian Khalid M. Noor; , Rimma Chanysheva; Awadalla H. KashifMalaria is most prevalent parasitic disease, it caused by coccidian parasite of the genus plasmodium, four species are usually infect human beings, P. falciparum, P. vivax, P. malriae and P. ovale, Most of malaria cases resulted from P. falciparum and P. vivax. Aryl hydrocarbon receptor (AHR) is an environmental sensor exists in many parts of human body such as lung, spleen, gut and breast. In this review we discussed the functions of it as regulator for proinflammatory and antiinflammatory cytokines, the possible role of diet during pregnancy and breastfeeding in boosting immunity against malaria during pregnancy and childhood by triggering AHR. Also we hypothesize that probable role of it in synchronizing erythrocytic schizogongy. Experimental studies recommended to know more about the biological protective functions of AHR.